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Title: Eugene Braunwald and the Rise of Modern Publisher: Harvard University Press, Cambridge. Since the s, the death rate from heart attacks has plunged from 35 percent to about 5 percent--and fatalistic attitudes toward this disease and many others have faded into history.

Legends of CV Medicine - Eugene Braunwald, MD, MACC

Much of the improved survival and change in attitudes can be traced to the work of Eugene Braunwald, MD. In the s, he proved that myocardial infarction was not a "bolt from the blue" but a dynamic process that plays out over hours and thus could be altered by treatment. By redirecting cardiology from passive, risk-averse observation to active intervention, he helped transform not just his own field but the culture of American medicine.

Braunwald's personal story demonstrates how the forces of history affected the generation of researchers responsible for so many medical advances in the second half of the twentieth century. In Nazi occupiers forced his family to flee Vienna for Brooklyn. Because of Jewish quotas in medical schools, he was the last person admitted to his class, but went on to graduate number one.

When the Doctor Draft threatened to interrupt his medical training during the Korean War, he joined the National Institutes of Health instead of the Navy, and there he began the research that made him the most influential cardiologist of his time.

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Lee offers insights that only authoritative firsthand interviews can provide, to bring us closer to this iconic figure in modern medicine. Eugene Braunwald and the Rise of Modern Medicine Much of the improved survival rate from heart attack can be traced to Eugene Braunwald's work. He proved that myocardial infarction was an hours-long dynamic process which could be altered by treatment.

The author tells the life story of a physician whose activist approach transformed not just cardiology but the culture of American medicine. Visit Seller's Storefront. We guarantee the condition of every book as it's described on the Abebooks web sites. If you've changed your mind about a book that you've ordered, please use the Ask bookseller a question link to contact us and we'll respond within 2 business days.

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Book Review: 'Eugene Braunwald and the Rise of Modern Medicine' by Thomas H. Lee - WSJ

If your book order is heavy or oversized, we may contact you to let you know extra shipping is required. List this Seller's Books. In , Braunwald moved to University of California at San Diego, where he dedicated himself to start a new cardiology research team, as he made great efforts for setting the best internal medicine teaching system in a new and growing medical school, in which he became the first internal medicine chairman. From California, Dr. There, he was involved to revolutionize the department, to remove the old people, and to populate the cardiology section with young, talented and ambitious physicians.


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He trained two generations of academics, who became very influential in academic medicine in various cities. He is the author of the open artery concept, which became fundamental for the treatment of acute myocardial infarction, he clarified the issue of unstable angina, postulated and demonstrated the role of lipid reduction in patients with CAD, and initiated the first major clinical trial TIMI Thrombolytics in Myocardial Infarction , which played a significant role in the progress of evidence based medicine philosophy.

Under Dr. The trial, which reached the TIMI phase, addressed to acute myocardial infarction therapy, many interventional procedures, pharmacodynamics of multiple cardiovascular drugs, the role of ACE inhibitors in cardiac disorders, MI biomarkers, genotypes and genomics, CAD prevention, and many others. Lee called Dr. Braunwald the most influential American cardiologist since Paul Dudley White PubMed stated that EB had more publications in the top general medical and cardiology journals than any of the more than Recently the famous cardiologist stated few advises for the young scientists: Young people who are contemplating a career in cardiovascular research should understand that we are now entering the most exciting period…It will take intensive training and powerful commitment to develop the skills required to move the field forward.

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